EXAM #1 Review Guide: Adv Patho
Fall 2019
1. Understand epigenetics and DNA methylation
2. Electrolyte disturbances, including causes, diagnosis and treatment
-Metabolic alkalosis
-Respiratory alkalosis
-Metabolic acidosis
-Respiratory acidosis
-Potassium, Sodium, Calcium, and Phosphate
3. Elements of formal genetics
4. Lead consumption adverse reaction to organs
5. Most common cause of cellular injury
6. Relationship of hyponatremia and diuretics
7. Cellular death
8. Multifactorial disorders
9. The Cell Cycle
10. Cellular adaptation
1. Atrophy, hypertrophy, hyperplasia and metaplasia
2. Maladaptive cellular change
11. Cellular structure and function of organelles
a. Nucleolus
b. mitochondria, lysosomes, ribosomes, etc
12. Cellular metabolism
13. Cellular membrane transport
Understand the Sodium- Potassium pump
14. Four major types of genetic diseases
a. Examples of recessive inheritance conditions
b. Hemoglobin types in Sickle Cell
15. Physiological effects of acute emotional stress
16. Genes related to Breast Cancer, Pancreatitis and Diabetes
17. Mitochondria, ATP and process of catabolism
18. Edema
19. Diffusion and osmosis
20. Hypernatremia and hyponatremia
21. Chromosomal Aberrations
a. Sex Chromosome Aneuploidy
b. Turner syndrome
22. Oncotic pressure
23. Water balance and ADH
24. Homeostasis
25. Concepts of Incidence and Prevalence
26. Renin-Angiotensin-Aldosterone system
27. Epigenetics and cancer
